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ATIKA Advanced Skin Nutrition — Clinical Ingredients & Mechanism Overview

ATIKA Advanced Skin Nutrition is a once-daily powdered formula with 18 clinically studied actives at evidence-based doses. It is designed as a foundational skin nutrition system to support:

  • Collagen structure and integrity
  • Barrier lipids and hydration
  • Antioxidant and photoprotective defense
  • Cellular energy and renewal

Formulated by Lily Shapiro, PharmD — nutritional dermatology & skin longevity.

Clinically Studied Actives per Daily Serving

One scoop daily in cold water. Always refer to the product label for the complete Supplement Facts panel.

Ingredient Amount per serving
VERISOL® collagen peptides
Supports dermal collagen structure, elasticity, and wrinkle depth in human studies.
2.5 g
Ceramosides™ wheat extract (phytoceramides)
Oral ceramides shown to improve hydration, elasticity, and reduce transepidermal water loss (TEWL).
30 mg
Sicilian Red Orange Complex™
Citrus polyphenols and carotenoids studied for support of photoprotection, redness, and tone.
100 mg
AstaReal® astaxanthin
Carotenoid associated with improvements in wrinkles, elasticity, and visible photodamage markers.
4 mg
Green tea extract (standardized for EGCG)
Catechins that support antioxidant defenses and modulation of collagen-degrading enzymes.
150 mg
Grape-seed extract (≥95% proanthocyanidins)
Oligomeric proanthocyanidins that support microvascular function, antioxidant capacity, and tone.
100 mg
Maqui berry fruit powder
Delphinidin-rich anthocyanins studied for photobiology and oxidative-stress support.
100 mg
Bamboo-derived silica
Source of silica to support collagen matrix, hair, and nail structure in oral studies.
100 mg
Lutein
Carotenoid that concentrates in skin and eyes and supports lipid-phase antioxidant defense.
10 mg
Zeaxanthin
Carotenoid that works with lutein in light-exposed tissues, including the skin.
2 mg
Lycopene
Tomato-derived carotenoid with human data for photoprotection and oxidative-stress support.
6 mg
Polypodium leucotomos extract
Fern extract studied for support of the skin’s response to UV exposure and oxidative stress.
480 mg
Vitamin C
Required cofactor for collagen synthesis and a central part of the internal antioxidant network.
500 mg
Vitamin A (as beta-carotene)
Supports epithelial integrity, healthy turnover, and photoaging-related pathways.
6,000 µg
Vitamin D
Plays a role in immune function and skin barrier-related biology.
25 µg
Niacinamide (vitamin B3)
Supports cellular energy pathways and redox balance relevant to skin.
500 mg
Zinc (as zinc picolinate)
Cofactor for antioxidant enzymes and collagen-related enzymes.
5 mg
Selenium
Essential for glutathione peroxidase and other antioxidant enzyme systems.
75 µg
MCTs and supporting excipients
Support mixability, palatability, and in some cases absorption of lipid-phase actives.
2 g

Other ingredients: natural flavors, citric acid, OnoSweet™ (Reb M), monk fruit extract. Contains wheat-derived Ceramosides™ (no gluten) and coconut-derived MCTs.

Four Biological Pathways of Skin Longevity

Advanced Skin Nutrition is structured around four biological pathways that naturally decline with age, UV exposure, oxidative stress, and midlife hormonal shifts. The goal is not surface “glow,” but support for the internal architecture that keeps skin resilient over time.

1. Collagen Structure & Integrity

Collagen begins to decline in our 30s. Fibroblast activity slows, oxidative damage accumulates, and cofactors for collagen synthesis are less consistently available.

  • VERISOL® collagen peptides (2.5 g) deliver bioactive peptides that signal fibroblasts to increase procollagen I and elastin.
  • Vitamin C (500 mg) is required to stabilize the collagen triple helix during synthesis.
  • Zinc (5 mg) and selenium (75 µg) support collagen-related enzymes and oxidative balance.
  • Silica (100 mg) supports collagen matrix structure and cross-linking.
  • Niacinamide (500 mg) and vitamin D (25 µg) support cellular energy and healthy turnover.

2. Barrier Lipids & Hydration

The skin barrier is rich in ceramides and other lipids that lock in moisture and maintain comfort. With age, ceramide levels fall, leading to dryness, roughness, and increased sensitivity.

  • Ceramosides™ (30 mg) provide oral ceramides shown to improve hydration, elasticity, and reduce TEWL in 15–60 days.
  • Niacinamide supports endogenous ceramide synthesis and barrier repair.
  • Carotenoids and polyphenols help protect those lipids from oxidative damage.

3. Antioxidant & Photoprotective Defense

UV and visible blue light generate reactive oxygen species (ROS) that degrade collagen, elastin, and barrier lipids. No single antioxidant can address every ROS type, which is why ATIKA uses a multi-antioxidant design.

  • AstaReal® astaxanthin (4 mg) supports elasticity, barrier function, and wrinkle appearance.
  • Red Orange Complex™ (100 mg) supports UV-induced redness, pigmentation, and antioxidant capacity.
  • Lutein (10 mg), zeaxanthin (2 mg), lycopene (6 mg) provide carotenoid defense against light-induced oxidative stress.
  • Green tea extract (150 mg), grape-seed extract (100 mg), maqui (100 mg) supply polyphenols that support antioxidant defenses and microcirculation.
  • Polypodium leucotomos (75 mg) supports the skin’s response to UV exposure.

These nutrients support the skin’s response to light and oxidative stress. They do not replace daily topical sunscreen.

4. Cellular Energy & Renewal

With age, NAD+ levels and mitochondrial efficiency decline, affecting how well skin can repair and renew itself.

  • Niacinamide (500 mg) supports NAD+ production and cellular energy.
  • MCTs (2 g) aid absorption of fat-soluble actives and support anti-inflammatory energy pathways.
  • Antioxidants and vitamin D help maintain a healthier environment for renewal.

Key Takeaways

  • ATIKA is built on 18 clinically studied actives at doses aligned with human data, not “fairy dust” amounts.
  • The formula supports four core pathways: collagen, barrier lipids, antioxidant defense, and cellular energy.
  • Results are gradual and cumulative: weeks for hydration and comfort; months for elasticity, tone, and fine-line appearance.
  • Advanced Skin Nutrition is designed as a foundational ritual that pairs with, not replaces, topical skincare and sun protection.

Safety, Quality & Use

  • Produced in a cGMP-certified facility in the United States.
  • Full, transparent Supplement Facts — no proprietary blends.
  • Contains wheat-derived ceramides (no gluten) and coconut-derived MCTs.
  • Formulated for adults; those who are pregnant, nursing, on medication, or with medical conditions should consult their clinician before use.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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