Advanced Skin Nutrition — Ingredients & Mechanisms
ATIKA Advanced Skin Nutrition is a once-daily powdered supplement containing 18 clinically studied actives at evidence-based doses. It is designed as a foundational skin nutrition system — not a single-ingredient product, not a topical, and not a quick-fix. It works from within, supporting the four biological pathways that govern how skin ages over time.
Results are gradual and cumulative. Hydration and comfort typically improve within weeks. Elasticity, tone, and fine-line appearance emerge over several months of consistent daily use — consistent with the timelines in the clinical literature for each ingredient.
All 18 Actives — Doses & Mechanisms
Per 10g scoop (one daily serving), mixed into cold water. Sweetened with OnoSweet™ (Reb M) and monk fruit extract.
| Ingredient | Dose |
|---|---|
| VERISOL® Collagen PeptidesCBioactive peptides that signal fibroblasts to increase procollagen I and elastin production. RCT-validated for improvements in skin elasticity and wrinkle depth. | 2.5 g |
| Ceramosides™ (wheat ceramides)LOral phytoceramides absorbed via the gut and delivered to skin cells responsible for barrier construction. Clinical trials show measurable reductions in transepidermal water loss (TEWL) within 15–60 days. | 30 mg |
| Polypodium leucotomos extractAFern extract with clinical evidence for supporting the skin's response to UV exposure and oxidative stress. One of the highest-dosed photoprotective botanicals in the category. | 480 mg |
| Niacinamide (Vitamin B3)MLDirect NAD⁺ precursor supporting cellular energy metabolism and DNA repair. Also supports endogenous ceramide synthesis and barrier lipid production. | 500 mg |
| Vitamin CCARequired cofactor for prolyl and lysyl hydroxylase — the enzymes that stabilize the collagen triple helix. Also a central aqueous-phase antioxidant and cofactor for vitamin E regeneration. | 500 mg |
| EGCG (green tea extract)ACatechins that support antioxidant defenses and modulate collagen-degrading enzymes (matrix metalloproteinases). | 150 mg |
| Bamboo SilicaCSource of silica supporting collagen matrix structure, cross-linking, and connective tissue integrity. Human studies also show benefits for hair and nail structure. | 120 mg |
| Red Orange Complex®ASicilian citrus polyphenols (flavanones, anthocyanins, hydroxycinnamic acids) studied for photoprotection, reduction of UV-induced redness, and support of skin tone evenness. | 100 mg |
| Grape Seed Extract (≥95% OPCs)AOligomeric proanthocyanidins supporting microvascular function, antioxidant capacity, and vascular and dermal oxidative defense. | 100 mg |
| Maqui BerryADelphinidin-rich anthocyanins with among the highest ORAC values of any fruit. Studied for photobiology and oxidative stress support. | 100 mg |
| LuteinACarotenoid that concentrates in skin and eyes. Supports lipid-phase antioxidant defense and blue light filtration in light-exposed tissues. | 10 mg |
| LycopeneATomato-derived carotenoid with human data for photoprotection and UV-induced oxidative stress support. Different pathway from astaxanthin. | 6 mg |
| AstaReal® AstaxanthinAPharmaceutical-grade carotenoid from Haematococcus pluvialis. Among the most potent singlet oxygen quenchers measured. Human studies show improvements in wrinkle appearance, elasticity, and visible photodamage markers. | 4 mg |
| ZeaxanthinAWorks with lutein in light-exposed tissues including skin. Supports carotenoid defense against light-induced oxidative stress. | 2 mg |
| Vitamin A (as beta-carotene)LRetinol precursor supporting epithelial integrity, healthy cell turnover, and photoaging-related pathways. Beta-carotene form avoids toxicity risk of preformed vitamin A at this dose. | 6,000 mcg |
| Vitamin DLSupports immune function, skin barrier biology, and barrier-related lipid synthesis. Widely deficient in the target population. | 25 mcg |
| Zinc PicolinateCHighly bioavailable zinc form. Cofactor for collagen cross-linking enzymes and matrix metalloproteinase regulation. Supports wound healing and antioxidant enzyme systems. | 5 mg |
| SeleniumAEssential cofactor for glutathione peroxidase and other antioxidant enzyme systems that protect skin cells from oxidative damage. | 75 mcg |
| MCT (medium-chain triglycerides)Supports mixability, palatability, and absorption of fat-soluble actives including carotenoids and astaxanthin. Coconut-derived. | 2 g |
Other ingredients: natural flavors, citric acid, OnoSweet™ (Reb M), monk fruit extract. Contains wheat-derived Ceramosides™ (no gluten) and coconut-derived MCTs.
Four Biological Pathways of Skin Longevity
Advanced Skin Nutrition is structured around four biological pathways that naturally decline with age, UV exposure, oxidative stress, and midlife hormonal shifts. The goal is not a surface effect but support for the internal architecture that keeps skin resilient over time.
Collagen production begins declining in the early 30s. Fibroblast activity slows, oxidative damage accumulates in the dermis, and the cofactors required for collagen synthesis are less consistently available from diet alone.
- VERISOL® collagen peptides (2.5g) deliver bioactive peptides that signal fibroblasts to increase procollagen I and elastin synthesis. Multiple RCTs show improvements in skin elasticity and wrinkle depth at this dose.
- Vitamin C (500mg) is a non-negotiable cofactor for prolyl and lysyl hydroxylase — the enzymes that stabilize the collagen triple helix during synthesis. Without adequate vitamin C, collagen synthesis stalls.
- Bamboo silica (120mg) supports collagen matrix structure and cross-linking. Human studies show benefits for skin, hair, and nail connective tissue.
- Zinc picolinate (5mg) supports collagen cross-linking enzymes and matrix metalloproteinase regulation. Picolinate form for bioavailability.
UV and visible light generate reactive oxygen species (ROS) that degrade collagen, elastin, and barrier lipids. No single antioxidant can address every ROS type or every tissue compartment. ATIKA uses a multi-antioxidant design spanning aqueous and lipid phases, carotenoid and polyphenol classes, and enzymatic support.
- AstaReal® astaxanthin (4mg) — pharmaceutical-grade, among the most potent singlet oxygen quenchers measured. Human studies show improvements in wrinkle appearance, elasticity, and photodamage markers.
- Red Orange Complex® (100mg) — Sicilian citrus polyphenols studied for photoprotection, reduction of UV-induced redness, and skin tone evenness.
- Polypodium leucotomos (480mg) — fern extract with clinical evidence for supporting the skin's response to UV exposure. One of the highest-dosed photoprotective botanicals in the ingestible category.
- Lutein (10mg), zeaxanthin (2mg), lycopene (6mg) — carotenoids concentrated in skin and eyes, providing lipid-phase defense against light-induced oxidative stress across different wavelengths.
- EGCG (150mg), grape seed extract (100mg), maqui berry (100mg) — polyphenols supporting antioxidant defenses, modulation of collagen-degrading enzymes, and microvascular function.
- Selenium (75mcg) — essential cofactor for glutathione peroxidase, the enzymatic antioxidant system that protects skin cells from oxidative damage.
- Vitamin C (500mg) — central aqueous-phase antioxidant and cofactor for vitamin E regeneration, in addition to its collagen role.
The skin barrier is rich in ceramides and other lipids that lock in moisture and maintain comfort. With age, ceramide levels fall — leading to dryness, roughness, increased sensitivity, and reduced efficacy of topical skincare. This is a structural problem, not a product problem, and it cannot be fully corrected from the outside.
- Ceramosides™ (30mg) — oral phytoceramides absorbed through the gut and delivered via the bloodstream to skin cells responsible for barrier construction. RCT data shows measurable reductions in transepidermal water loss and improvements in hydration and skin texture within 15–60 days.
- Niacinamide (500mg) — supports endogenous ceramide synthesis and barrier lipid production in keratinocytes, in addition to its cellular energy role.
- Vitamin D (25mcg) — supports immune function and barrier-related lipid synthesis. Deficiency is common in the target population.
- Vitamin A as beta-carotene (6,000mcg) — retinol precursor supporting epithelial integrity and healthy cell turnover. Beta-carotene form avoids toxicity risk at this dose.
With age, NAD⁺ levels and mitochondrial efficiency decline, affecting how well skin can repair, renew, and maintain itself. Cellular energy is the substrate for nearly every repair process in skin — collagen synthesis, barrier reconstruction, and DNA repair all depend on it.
- Niacinamide (500mg) — a direct NAD⁺ precursor. NAD⁺ is a coenzyme central to cellular energy metabolism, mitochondrial function, and DNA repair. Both decline measurably with age and limit skin's capacity to renew itself.
- MCT (2g) — supports absorption of fat-soluble actives including carotenoids and astaxanthin, and contributes to anti-inflammatory energy pathway support.
- The antioxidant constellation supports a lower oxidative burden on mitochondria, preserving repair capacity over time.
- 18 clinically studied actives at doses aligned with human data — not token amounts.
- Four pathways addressed simultaneously: collagen structure, barrier lipids, antioxidant defense, and cellular energy.
- Results are gradual: weeks for hydration and comfort, months for elasticity, tone, and fine-line appearance.
- Designed as a foundational daily ritual that pairs with — not replaces — topical skincare and sun protection.
- No proprietary blends. Full ingredient and dose transparency.
Frequently Asked Questions
How long does it take to see results?
Results are gradual and cumulative. Hydration and skin comfort improvements have been observed within 15 to 60 days in ceramide studies. Improvements in elasticity, tone, and fine-line appearance typically emerge over several months of consistent daily use, consistent with the timelines in collagen peptide and antioxidant research. Individual responses vary.
Does this replace sunscreen?
No. ATIKA's antioxidant and photoprotective ingredients — including Polypodium leucotomos, carotenoids, and polyphenols — support the skin's internal response to light and oxidative stress. They do not replace daily topical sunscreen, which remains the primary intervention for UV protection.
Does this replace topical skincare?
No — it complements it. Topical products work at and above the barrier. ATIKA works from within, addressing biological mechanisms that topicals cannot reach: collagen fibroblast signaling, oral ceramide delivery, internal antioxidant defense, and cellular energy. The two layers work together, not against each other.
Why a powdered formula rather than capsules?
The therapeutic doses required across 18 actives — including 2.5g of collagen peptides and 2g of MCT — cannot fit in a practical capsule count. A powder also allows for better mixability of both water-soluble and fat-soluble ingredients in a single serving, and the MCT carrier supports absorption of lipid-phase actives including carotenoids and astaxanthin.
Is this safe to take with other supplements?
Advanced Skin Nutrition contains vitamins A, C, D, B3, zinc, and selenium, which should be considered when combining with a multivitamin to avoid excessive intake of any single nutrient. Those on medication, pregnant, nursing, or with medical conditions should consult their clinician before use.
Manufacturing & Use
- Produced in a cGMP-certified facility in the United States.
- Full, transparent Supplement Facts — no proprietary blends, no hidden doses.
- Contains wheat-derived Ceramosides™ (no gluten) and coconut-derived MCTs.
- Those who are pregnant, nursing, on medication, or with medical conditions should consult their clinician before use.
- Consider vitamin and mineral content when combining with a daily multivitamin.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Individual responses to supplementation vary. This page is intended for educational purposes and does not constitute medical advice. Consult a qualified clinician for personalized guidance.